Hong Kong Training Portal on
Infection Control and Infectious Disease

Epidemiology

• Pneumococcal infection in adults: burden of disease. (2014 May).
• Epidemiological differences among pneumococcal serotypes. (2005 Feb 1)
• Pneumococcal disease in western Europe: burden of disease, antibiotic resistance and management. (2002 Apr 1)
• Impact of the use of heptavalent pneumococcal conjugate vaccine on disease epidemiology in children and adults. (2006 Apr 12)
• Changing epidemiology of invasive pneumococcal disease among older adults in the era of pediatric pneumococcal conjugate vaccine. (2005 Oct 26)

Clinical Information and Management

• Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America (Oct 1, 2019)
• Current status and future directions of invasive pneumococcal diseases and prophylactic approaches to control them (18 Jun 2018)
• The influence of chronic illnesses on the incidence of invasive pneumococcal disease in adults. (2005 Aug 1)
• Streptococcus pneumoniae colonisation: the key to pneumococcal disease. (2004 Mar 1)
• Cigarette smoking and invasive pneumococcal disease. ( 2000 Mar 9)

Associated Complications

• Rates of, and risk factors for, septic arthritis in patients with invasive pneumococcal disease: prospective cohort study.(2017 Dec)
• Cardiotoxicity during invasive pneumococcal disease. (2015 Apr 1)

Vaccination

• Pneumococcal ACIP Vaccine Recommendations - CURRENT Recommendations
• How Should We Use Conjugate Pneumococcal Vaccine in Immunocompetent Older Adults? (July 25, 2019)
• Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults. (2015 Mar 19)
• Effect of use of 13-valent pneumococcal conjugate vaccine in children on invasive pneumococcal disease in children and adults in the USA: analysis of multisite, population-based surveillance. (2015 Mar 1)
• Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study. (2015 May 1)
• Vaccines for preventing pneumococcal infection in adults. (2013)
• Sustained reductions in invasive pneumococcal disease in the era of conjugate vaccine. (2010 Jan 1)

Serotype replacement

• Pneumococcal serotype trends, surveillance and risk factors in UK adult pneumonia, 2013-18 (2020 Jan)
• Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study (June 10, 2019)
• Serotype replacement in disease after pneumococcal vaccination. (2011 Dec 3)

Antimicrobial susceptibility

• Rising Pneumococcal Antibiotic Resistance in the Post–13-Valent Pneumococcal Conjugate Vaccine Era in Pediatric Isolates From a Primary Care Setting (18 February 2020)
• Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae. (2006 Apr 6)